Mononucleosis infecciosa pdf 2010

Infectious mononucleosis is the name coined by sprunt and evans in 1920 1 for an acute infectious disease consisting of fever, cervical lymphadenopathy and pharyngitis accompanied by atypical large peripheral blood lymphocytes. Treatment is symptomatic and there is not a specific antiviral medicine. See page 1201 for definitions of strengthofrecommendation labels. Infectious mononucleosis im is characterized by a triad of fever, tonsillar pharyngitis, and lymphadenopathy. Infectious mononucleosis as a potential risk to the dentist. Infectious mononucleosis syndrome in adolescents and adult patients infectious mononucleosis syndrome, characterized in typical cases by fever, sore throat, tonsillar exudates, cervical adenopathies and atypical lymphocytosis is associated in most cases to epsteinbarr. The virus spreads through saliva, which is why its sometimes called kissing disease. Im includes the other causes of mononucleosis syndrome. A handout on infectious mononucleosis, written by the author of this article, is provided on page 1289. In addition to causing acute illness, longterm consequences are. The epidemiology of infectious mononucleosis in northern.

Im is a clinical syndrome caused by epsteinbarr virus. Infectious mononucleosis mono mono symptoms medlineplus. A 16yearold, previously healthy girl presents with a severalday history of fever, sore throat, and malaise. Pattisons editorial prompts us to report recent difficulties that we encountered. Evolution of ebv or cmv infection is favorable with infrequent complications. Infection with epsteinbarr virus ebv is almost ubiquitous in humans and generally occurs at two ages. Characteristically it consists of fever, lymphadenopaty and acute pharyingitis and ocasionally it will also present. Assessing highresolution melt curve analysis for accurate detection of gene variants in complex dna fragments. Whereas most ebv infections of infants and children are. Most people are infected by the virus as children, when the disease produces few or no symptoms. Infectious mononucleosis, or mono, is an infection usually caused by the epsteinbarr virus. Taylor gh 2003, wang x 2010, candy b 2002, luzuriaga k 2010, jenson hb 2011.

Mononucleosis infecciosa infectious mononucleosis dra. We now know that the characteristic atypical lymphocytes, carefully described morphologically by downey and. In young adults, the disease often results in fever, sore throat, enlarged lymph nodes in the neck, and tiredness. Infectious mononucleosis im, mono, also known as glandular fever, is an infection usually caused by the epsteinbarr virus ebv. Infectious mononucleosis disease fact sheet spanish. It was initially described as drusenfieber or glandular fever in 1889, but the term infectious mononucleosis was later used in 1920 to describe six college students with a febrile illness characterized by absolute lymphocytosis and atypical mononuclear cells in. The new england journal of medicine n engl j med 362. Tindall ea, petersen dc, woodbridge p, schipany k, hayes vm. She appears very tired and has a temperature of 39c. Ebvspecific antibody profiles are the best choice for staging ebv infection. Infectious mononucleosis im is a widely spread systemic viral disease caused in 90% of cases by the epsteinbarr virus evb and approximately 95% of the adult population is ebvseropositive. Acute hepatitis due to infectious mononucleosis in a 21.